Fantasy football managers know that every lineup decision can make or break a week, and choosing the right players to start or sit is where championships are won. With the 2025 NFL season underway, matchups, stats, and trends are more important than ever. From favorable matchups and scoring trends to players you should avoid in tough spots, my weekly positional start and sit guide is built to give you an edge.
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Wide Receivers to Start
Emeka Egbuka TB
Emeka Egbuka should be locked into fantasy lineups this week with Mike Evans sidelined and Chris Godwin’s status in question. The rookie has been a model of consistency, scoring at least 12.9 PPR points in every game and finding the end zone three times through three weeks. He now leads Tampa Bay in receiving yards, touchdowns, and passer rating when targeted. The matchup also works in his favor. Philadelphia has already allowed four receivers to score 13.9+ PPR points, and Baker Mayfield threw for 347 yards and two TDs against them last year. With his growing target share and ability to separate both inside and outside, Egbuka is a lineup lock heading into Week 4.
Jakobi Meyers LV
Jakobi Meyers had a down week last week, finishing with 9.3 points, but has failed to go under 63 receiving yards in a game this year. He leads the Raiders in targets and owns a 22.6% target share with nearly 2.0 yards per route run. Chicago’s defense sets up perfectly for Meyers’ role, as they run two-high shells at the third-highest rate, a look where Meyers’ target share jumps to 27% to 39%. The Bears have also given up the third-most fantasy points to wide receivers, including some big-time performances from the slot. Coming off a down Week 3, Meyers is in line for a bounce-back and should be locked into lineups this week.
Keenan Allen LAC
Keenan Allen remains the engine of the Chargers’ passing attack and is an automatic fantasy football start in Week 4. He has posted at least 17.1 PPR points in every game so far while averaging over nine targets per outing. The Giants have been shredded by wide receivers, allowing the second-most fantasy points to the position and five different players to top 15.3 PPR points already. Allen’s route volume and efficiency give him both floor and ceiling, while Ladd McConkey and Quentin Johnston also carry upside in this matchup. Fantasy managers should continue to feel confident in the Chargers’ receivers this week.

Wide Receivers to Sit
Tee Higgins CIN
Tee Higgins has become a frustrating fantasy football option with Joe Burrow sidelined, and Week 4 doesn’t look much better. Outside of a 42-yard touchdown in Week 2, Higgins has just six catches for 62 yards on the year, averaging fewer than three receptions and 35 yards per game. Backup QB Jake Browning has struggled, throwing five interceptions in under two full games while failing to support his receivers’ fantasy production. Denver’s secondary has also been stingy, allowing just one WR touchdown and holding opposing wideouts to a 56% catch rate. Higgins is best left on the bench and should not be started outside of deep three-WR fantasy football formats.
Calvin Ridley TEN
Calvin Ridley’s struggles have made him one of the biggest disappointments in fantasy football. He has just eight catches on 21 targets through three weeks, averaging 37 yards per game and scoring fewer than 9 PPR points each outing. His efficiency metrics are alarming, ranking bottom five in separation and route win rate, showing he isn’t consistently creating space. The matchup doesn’t help either, as Houston has allowed the eighth-fewest points per target to perimeter receivers. Until Ridley shows signs of life with rookie QB Cam Ward, he’s a must-sit in fantasy football lineups, and managers should only keep him rostered for upside potential later in the season.
DK Metcalf PIT
D.K. Metcalf has scored in back-to-back games, but his underlying production has been shaky, averaging just 45 receiving yards per contest with a 19% target share. His per-route efficiency is even more concerning, ranking last among qualifying WRs in separation and outside the top 50 in route win rate. This week, he faces a nightmare matchup against Minnesota, who allow the third-fewest fantasy points to perimeter receivers and has shut down names like Ja’Marr Chase and Drake London. Another note, without a lack of playmakers at receiver around Metcalf, Minnesota will gameplan about slowing Metcalf down. Managers should sit Metcalf in Week 4 fantasy football lineups, with his value capped as a low-end WR3.