Fantasy football managers know that every lineup decision can make or break a week, and choosing the right players to start or sit is where championships are won. With the 2025 NFL season underway, matchups, stats, and trends are more important than ever. From favorable matchups and scoring trends to players you should avoid in tough spots, my weekly positional start and sit guide is built to give you an edge.
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Quarterbacks to Start
Brock Purdy SF
Brock Purdy has been steadily productive since returning from injury, delivering the kind of weekly consistency fantasy football managers value this time of year. His workload has remained stable, and San Francisco’s offense has looked increasingly in rhythm as his supporting cast has gotten healthier. Purdy’s efficiency has been strong throughout the season, with multiple games falling in that safe 17-to-19 point range that keeps fantasy lineups afloat. The 49ers have also leaned into a balanced approach that allows him to operate comfortably within structure. With improved health and a full arsenal of weapons around him, Purdy looks positioned to take another step forward. The matchup further enhances the environment he’ll be working in, helping lift his ceiling beyond what we’ve seen in recent weeks.
That brings him into start territory for Week 15, as the Titans present one of the most favorable setups for opposing quarterbacks. Tennessee has been among the most vulnerable pass defenses in football since Week 10, ranking top six in pass yards and passing touchdowns allowed while also sitting top four in passer rating allowed. They were just carved up by Shedeur Sanders for more than 28 fantasy football points and four total touchdowns, signaling that explosive performances against them aren’t outliers. Purdy already carries a safe weekly floor, but this matchup elevates his ceiling into top-five potential. Six of the past seven quarterbacks to face Tennessee have delivered at least 18 points, and their struggles align perfectly with Purdy’s offense trending in the right direction. In a week where managers need reliability with upside, he profiles as a strong fantasy football start across all formats.
Jaxson Dart NYG
Jaxson Dart enters Week 15 having shown strong command of the Giants offense since stepping into the starting role, even if last week’s fantasy output dipped below his usual standards. His dual-threat ability continues to give him a stable foundation, as he has remained committed to running despite a quieter passing performance. Before last week, he had averaged 21.7 fantasy PPG as a starter and showcased reliable volume both through the air and on the ground. Dart’s confidence as a runner and willingness to push the ball downfield have helped preserve his weekly value. The bye week should also allow the offense to reset and get him back into a comfortable rhythm. Considering the context and his underlying usage, Dart still profiles as a quarterback capable of bouncing back quickly.
That brings him into start consideration this week against a Commanders defense that has struggled badly against quarterbacks. Washington has allowed 18 or more fantasy points to the position nine different times, and just let J.J. McCarthy produce over 20 points with three passing touchdowns. They rank top five in passing yards, passing touchdowns, and fantasy points per game allowed to quarterbacks, consistently giving up explosive plays. Dart has finished with at least 18 points in six of his past eight fully healthy outings, and this matchup aligns well with his strengths as both a passer and runner. Given how vulnerable Washington is on the back end, Dart projects as a top-10 fantasy football start this week. His rushing floor, paired with the Commanders’ defensive issues, makes him an appealing option in all scoring formats.
Trevor Lawrence JAC
Trevor Lawrence has grown increasingly comfortable within Liam Coen’s offense over the past several weeks, rounding into form at the right time for fantasy football managers. Since Week 9, he has performed as the QB9 while delivering multiple QB1 finishes, highlighted by sharp accuracy and improved decision-making. His efficiency metrics tell the story: he ranks ninth in yards per attempt, 14th in highly accurate throw rate, and 12th in catchable target rate among qualifying quarterbacks in that span. Lawrence has also quietly gotten better at leveraging his mobility to extend plays without forcing throws this season. Jacksonville’s offense has leaned on him more as the season progresses, and his timing with the receiving corps has noticeably improved as they are close to healthy. Even minor injury concerns this week appear minimal based on his practice participation and media availability.
All of that leads him into start territory against a Jets defense that has not performed nearly as well against quarterbacks lately. Since Week 10, New York has allowed the ninth-highest success rate per dropback, the ninth-highest EPA per dropback, and the 12th-highest passer rating, signaling a clear regression from their early-season form before the trade deadline. Lawrence has scored at least 18 fantasy football points in three straight games, giving him strong momentum entering this matchup. While the Jaguars’ run game may find success, Lawrence’s efficiency and touchdown production over the last few weeks may be too much to overlook. His combination of accuracy, rhythm, and recent volume keeps him firmly on the QB1 radar. Lawrence should be viewed as a comfortable start with low-end QB1 potential across all leagues.
Quarterbacks to Sit
Caleb Williams CHI
Caleb Williams enters Week 15 coming off another underwhelming fantasy performance, continuing a trend that has made him difficult to trust in consistent lineups. He has failed to reach 15 fantasy points in three of his last four games and five of his last eight, reflecting a concerning floor for a quarterback expected to grow in year one under Ben Johnson. The passing efficiency issues are noticeable, as he ranks 33rd in completion percentage and 23rd in passer rating among qualified quarterbacks. Chicago’s offense has also shifted toward a run-first identity, which limits Williams’ weekly volume and reduces his margin for error. With Rome Odunze potentially sidelined again, his receiving corps may enter this matchup short-handed. The combination of stagnating production, passing inconsistency, and reduced opportunity share creates a fragile setup heading into the week.
Those factors push him firmly into sit territory for Week 15 against the Browns, who remain one of the toughest defenses in fantasy football. Cleveland has allowed the sixth-fewest fantasy points to quarterbacks and has held five straight passers to 19.3 points or fewer. They carry the second-highest sack rate in the league and have surrendered the fifth-fewest passing yards since Week 10, creating an environment where explosive plays are scarce. Chicago’s run-heavy approach only narrows Williams’ path to value further, especially if the Bears control the game script. With a lower floor than virtually any streaming option this week, Williams should be avoided outside of Superflex formats. He profiles as a clear sit in one-quarterback leagues.
Jacoby Brissett ARI
Jacoby Brissett has been one of the season’s biggest surprises, delivering at least 18 fantasy points in eight straight games while stabilizing Arizona’s offense following Kyler Murray’s injury. His processing has been sharp, his efficiency has held up against strong opponents, and his accuracy has allowed the Cardinals’ offense to find some rhythm in the passing game. Even in tough matchups against teams like the Rams, Seahawks, and Packers, he found ways to produce fantasy-relevant numbers. Arizona’s scheme has leaned heavily on his consistency, and his rapport with the receiving corps has been a major asset. However, the loss of left tackle Paris Johnson looms large heading into this week, reducing protection on Brissett’s blind side. It introduces a new layer of volatility at a time when matchups matter more than ever.
That volatility is one of several reasons he moves into sit territory this week against the Texans, who are the league’s toughest fantasy football matchup for quarterbacks. Houston has allowed the fewest fantasy points, the fewest passing touchdowns, and the fifth-fewest passing yards to the position this season. They’ve intercepted more passes than they’ve allowed touchdowns, joining only the Chargers in that category. Over the last three weeks alone, they held Josh Allen and Patrick Mahomes to fewer than nine fantasy points combined, without giving up a single touchdown pass. With Houston’s offense typically playing slow and low-scoring, the chance for garbage-time production is minimal. Brissett remains a viable Superflex option, but in standard formats, he is a recommended sit.
Bo Nix DEN
Bo Nix remains one of the most volatile quarterbacks in fantasy football, with his overall season average buoyed heavily by a massive Week 7 performance. Since Week 8, he has not logged a single QB1 finish, and his weekly production has dipped to 18.4 points or fewer in four straight games. His per-dropback numbers paint a similar picture: while he ranks 12th in highly accurate throw rate, eighth in catchable target rate, and 15th in hero throw rate since Week 9, he still sits 31st in yards per attempt and 31st in passer rating. The disappearance of his rushing floor has also contributed to his decline, as he has managed only 73 rushing yards and one rushing touchdown across his last five outings. The statistical profile continues to point towards volatile outcomes despite the volume for Nix.
That lack of reliable fantasy production makes him a strong sit candidate this week against a tough Packers defense. Since Week 10, Green Bay has allowed the seventh-fewest passing yards, the 11th-lowest success rate per dropback, and the 14th-lowest passer rating while generating one of the league’s highest pressure rates. Only one quarterback has topped 18.9 fantasy football points against them in the past six weeks, despite matchups with Jalen Hurts and Caleb Williams. With Nix failing to score multiple touchdowns since Week 9 and offering almost nothing on the ground, the path to a meaningful fantasy performance is narrow. His perfect record and efficiency against NFC opponents is interesting but not actionable in a matchup this difficult. In one-quarterback leagues, Nix should remain firmly on the bench.
