Fantasy football managers know that every lineup decision can make or break a week, and choosing the right players to start or sit is where championships are won. With the 2025 NFL season underway, matchups, stats, and trends are more important than ever. From favorable matchups and scoring trends to players you should avoid in tough spots, my weekly positional start and sit guide is built to give you an edge.
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Quarterbacks to Start
Caleb Williams CHI
Caleb Williams continues to look like a must-start in fantasy lineups. He torched Dallas in Week 3 with 298 passing yards and four touchdowns, finishing as the overall QB1 while avoiding a single sack for the first time in his young career. Williams is averaging 23.4 PPG this season and now draws a favorable matchup against the Raiders. Las Vegas has created pressure at one of the lowest rates in the NFL and sits in the bottom 10 in passing yards and passer rating allowed. With the Bears’ offense starting to find its rhythm and Williams’ confidence growing, fantasy managers should confidently start Williams as a top-five quarterback this week.
Geno Smith LV
Geno Smith’s underlying efficiency metrics aren’t great, but volume and matchup make him a strong start in Week 4 fantasy football. He ranks fourth in passing yards per game and eighth in attempts, and he’s coming off a 289-yard, three-touchdown performance against Washington. Now, he gets a Bears defense that has surrendered the third-most fantasy points to quarterbacks, including big games from Jared Goff and J.J. McCarthy. Chicago also allows the seventh-highest passing yards per game and the sixth-highest yards per attempt. With this matchup setting up as a shootout opposite Caleb Williams, fantasy managers should start Smith as a top-10 quarterback in all formats.
Jordan Love GB
Jordan Love had a rough Week 3 against Cleveland, but the Browns boast one of the league’s best defenses. This week is the exact opposite, as he faces a Cowboys unit that has allowed the most fantasy points per game to quarterbacks. Over the past two weeks, Dallas gave up a combined 748 passing yards and seven touchdowns to Russell Wilson and Caleb Williams. Love has a history of thriving in favorable matchups, and Sunday Night Football provides the stage for another bounce-back performance. With Dallas’ defense struggling in coverage and failing to generate consistent pressure, fantasy managers should start Love confidently as a top-10 quarterback this week.
Quarterbacks to Sit
Dak Prescott DAL
Dak Prescott has struggled to provide reliable fantasy production, with only one game above 12 points this season. He enters Week 4 with just three touchdown passes and the same number of interceptions, and now he’ll be without key weapons, including CeeDee Lamb and multiple starters along the offensive line. The matchup against Green Bay is brutal; the Packers have allowed the third-fewest fantasy points to opposing quarterbacks while creating pressure at an above-average rate. With limited upside and a tough defensive opponent, fantasy managers should sit Prescott in all formats this week, even in Superflex leagues.
Aaron Rodgers PIT
Despite ranking as a fringe QB1 in points per game, Aaron Rodgers’ efficiency has been alarming. He sits bottom 10 in completion percentage over expected, catchable target rate, and air yards per attempt, relying on an unsustainable touchdown rate to buoy his fantasy numbers. That inefficiency is likely to be exposed against Minnesota, a defense ranking top-10 in fewest passing yards allowed while also generating the second-highest pressure rate in the NFL. Rodgers has failed to top 12 fantasy points in two straight games, and the Vikings’ blitz-heavy scheme is a bad matchup for his declining mobility. Fantasy managers should sit Rodgers in Week 4.
Daniel Jones IND
Daniel Jones has been one of the early surprises in fantasy football, averaging 22.7 points per game through three weeks. However, this matchup against the Rams is where regression could hit. Los Angeles ranks fifth in pressure rate, and Jones has historically struggled under duress, carrying a career passer rating under 70 when pressured. The Rams held both C.J. Stroud and Cam Ward in check earlier this year, while bottling up the Eagles’ offense for most of Sunday’s game. With this game on the road, Jones profiles as more of a QB2 option. Fantasy managers should sit Jones in standard leagues and only use him in Superflex formats.
